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Resveratrol Improves Mitochondrial Capacity

Here's another study that confirms the mitochondrial benefits of resveratrol, where it boosted the mitochondrial capacity when it was combined with exercise.

Although it's only a small pilot-style study, it does add something useful to the developing body of evidence. For this study, researchers studied 16 young adults who were put on a low-intensity exercise program and found that participants that ingested 500 mg of resveratrol (plus 10 mg of piperine, an alkaloid found in black peppers, to help with absorption) daily over four weeks, had a significant increase in skeletal muscle mitochondrial capacity compared to participants who ingested a placebo.

It's important to note that exercise was an important part of the study, as researchers sought to find out the effect of ingesting resveratrol with submaximal endurance training in healthy subjects. For this study, the exercise sessions consisted of 30 minutes of forearm wrist flexor exercises three times per week over four weeks.

“The wrist flexor muscles were chosen as the muscle of interest because they are relatively de-trained,” the researchers wrote. The dominant arm was not trained and used as the untrained control arm for each subject.

The results showed a significant 40% increase in mitochondrial capacity in the resveratrol arm from the baseline. The placebo-trained arm, which saw a 10% increase from the baseline.

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Source: Influence of exercise training with resveratrol supplementation on skeletal muscle mitochondrial capacity

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