Welcome!


Thanks for visiting! My goal here is to discuss the latest scientific research to separate the good from all that "guff" in nutritional sciences and all aspects of human health. Because the more you Know, well...the more you Know!

Looking for a specific post? You can browse the Most Read Posts, the Blog Archives, or use the Search function in top left of this page. Thanks for your support and stay healthy!

Monthly 3D Poll

2015-02-25

Kidney Stones Linked to Higher Risk for Arterial Calcification

So last week I posted the study on vitamin K2 showing the potential to reverse arterial calcification. Here is a newly published related study. I should point out that back in 2011, I discussed the potential role of vitamin K in preventing calcium kidney stones (click HERE for that study), and now this study adds considerably more evidence to that train of thought.

Essentially, this study found that patients who form calcium kidney stones are more likely to have higher abdominal aortic calcification (AAC) and lower vertebral bone mineral density (BMD) scores than those who do not develop kidney stones.

The researchers found that the prevalence of AAC was similar in patients who formed kidney stones (38%) compared with in non-stone forming control patients (35%). However, 68%, of kidney stone formers (KSFs) had moderate to severe AAC scores compared with only 26% of non-stone forming controls. The average BMD was also significantly lower in patients with a history of kidney stones compared with those who did not.

"[M]ultivariate analyses adjusted for all potential confounders confirmed that kidney stone disease is independently associated with advanced forms of [vascular calcification] compared with non-KSF" the study's authors said.

"Our study demonstrates that patients with calcium kidney stones suffer from significantly higher degrees of aortic calcification than age- and sex-matched non-stone formers," they wrote, "suggesting that [vascular calcification] may be an underlying mechanism explaining reported associations between nephrolithiasis and [cardiovascular disease]."

Again, I can't help but think this connection is so obvious that it slaps me in the face. Yeah, right in the face. As I mentioned in my previous post, nephrocalcin (found in the kidneys), osteocalcin (in the bones), and MGP (in the arteries) are all vitamin K-dependent proteins. As long as you get enough vitamin K2 (and most people don't actually get enough), these proteins will be activated and you can ensure the calcium goes into the right places (the bones, and not arteries or kidney stones).

Unfortunately, many researchers are very narrowly focused and can't make those connections... so they continue to look for a mechanism and will spend millions of dollars and years of their life answering the question of "why" this link exists.

Click HERE to subscribe to Know Guff.

Source: Vascular Calcification and Bone Mineral Density in Recurrent Kidney Stone Formers

Related posts:

1 comment:

  1. Kidney stones have many causes and can affect any part of your urinary tract — from your kidneys to your bladder. Often, stones form when the urine becomes concentrated, allowing minerals to crystallize and stick together.

    Passing kidney stones can be quite painful, but the stones usually cause no permanent damage. Depending on your situation, you may need nothing more than to take pain medication and drink lots of water to pass a kidney stone.

    Your doctor may recommend preventive Kidney Stones Treatment to reduce your risk of recurrent kidney stones if you're at increased risk of developing them again. Thanks

    ReplyDelete

Please use your name or alias. Due to a large volume of spam comments (as "Anonymous") all comments from "Anonymous" will be automatically deleted. Thanks.