According to this study on mice, researchers at the National Cancer Institute (NCI) in the US found that tumors of bacteria-free mice (mice completely lacking these microorganisms), or mice treated with antibiotics to deplete the gut of bacteria, showed an impaired response to immunotherapy that slows cancer growth and prolongs survival. The mice also had an impaired ability to respond to popular chemotherapy drugs such as oxaliplatin and cisplatin.
These findings in mice may indicate the importance of microorganisms in the optimal response to cancer treatment in humans. As I mentioned in my previous post discussing biotransformation, humans harbour microorganism in the gut that can not only influence local and whole-body health and disease, but these little friends can also modify the tumour microenvironment (which consists of a variety of cell types, signaling molecules, and other mechanisms that may support tumour growth and/or influence drug resistance.
The probiotic industry has great products to boost the microbial content of the gut after antibiotic use, but it's ignorant to think these products can return the gut to its pre-antibiotic health.
So stop using antibacterial products, and use antibiotics only when absolutely needed.
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Source: Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment
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