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Vitamin K Improves Memory

So on Friday, I co-delivered a presentation on PQQ with the global authority on PQQ, Dr. Masahiko Nakano. For those who were able to attend, thank you for your participation in making the event a success! While PQQ is amazing for memory, today's study of discussion is on vitamin K's role in memory and cognition.

Back in 2011, I covered an animal study linking vitamin K to cognitive health and another study linking arterial calcification (a result of low vitamin K status) to dementia. Now here is another study showing K's potential brain benefits.

Data from 320 participants in the Qu├ębec Longitudinal Study on Nutrition and Successful Aging (NuAge), researchers found that higher plasma phylloquinone (vitamin K1) levels were associated with better verbal episodic memory performance, including the 20-minute delayed free recall trials (but no links were found between phylloquinone levels and other measures of cognitive function).

"Episodic memory" is the memory of events within a space-time context (for example, remembering where you left your iPhone), so it's an aspect of cognition important to everyday life.

As for the potential mechanism, the researchers stated that “the vitamin K-dependent proteins Gas6 (growth arrest-specific gene 6) and protein S are expressed in the central nervous system. Protein S is notably known to possess neuroprotective effects during hypoxic/ischemic injury, whereas Gas6 is now recognized as an important regulator of cell survival, cell growth, and myelination processes.

Furthermore, vitamin K participates in the metabolism of sphingolipids, a major constituent of the myelin sheath and neuronal membranes, also involved in important molecular events such as cell signaling.

So if you haven't been taking vitamin K yet, click HERE and subscribe to Know Guff before you forget where you put your iPhone, iPad, laptop, or whatever you're using to read this.

Source: Vitamin K status and cognitive function in healthy older adults

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  1. Thanks for information. Maybe this study explains why students are told to eat fresh food. Have you by the way found any research concerning fibromyalgia and vitamin K2? Vitamin K dependent Gla-rich protein (GRP) may be the key to heal it.

    1. I think there are countless benefits of eating fresh food, and vitamin K is just a fraction of their benefit, but it does raise some interesting hypotheses.

      Regarding K2 for fibromyalgia, no, I have not heard of this, but it'd be fascinating to know more if you're able to share more info here. Thanks for your input!


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