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Olive Leaf Extract Improves Insulin Sensitivity

Here's a short summary of a human study on an ingredient I don't see studied very often--olive leaf extract (OLE).

In a randomized, double-blind, placebo-controlled, crossover trial involving 46 middle-aged, overweight men, supplementation with OLE (51.1 mg oleuropein and 9.7 mg hydroxytyrosol per day) for a period of 12 weeks was found to be associated with a 15% improvement in insulin sensitivity, as compared to placebo.

In addition, a 28% improvement in pancreatic beta-cell responsiveness, and increased fasting interleukin-6, IGFBP-1, and IGFBP-2 concentrations were found. 

The authors conclude, "Supplementation with olive leaf polyphenols for 12 weeks significantly improved insulin sensitivity and pancreatic beta-cell secretory capacity in overweight middle-aged men at risk of developing the metabolic syndrome."

Source: Olive (Olea europaea L.) Leaf Polyphenols Improve Insulin Sensitivity in Middle-Aged Overweight Men: A Randomized, Placebo-Controlled, Crossover Trial

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