Here's a short summary of a human study on an ingredient I don't see studied very often--olive leaf extract (OLE).
In a randomized, double-blind, placebo-controlled, crossover trial involving 46
middle-aged, overweight men,
supplementation with OLE (51.1 mg oleuropein and 9.7 mg
hydroxytyrosol per day) for a period of 12 weeks was found to be associated with
a 15% improvement in insulin sensitivity, as compared to placebo.
In addition, a
28% improvement in pancreatic beta-cell responsiveness, and increased fasting
interleukin-6, IGFBP-1, and IGFBP-2 concentrations were found.
The authors conclude, "Supplementation with olive
leaf polyphenols for 12 weeks significantly improved insulin sensitivity and
pancreatic beta-cell secretory capacity in overweight middle-aged men at risk of
developing the metabolic syndrome."
Source: Olive (Olea europaea L.) Leaf Polyphenols Improve Insulin Sensitivity in Middle-Aged Overweight Men: A Randomized, Placebo-Controlled, Crossover Trial
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