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DHA (Omega-3) & Vitamin D Clear Plaques in Alzheimer's Disease

So I've covered a few similar studies in the past, both on omega-3's and vitamin D's beneficial effects on helping to clear amyloid beta plaques, which are a hallmark of Alzheimer's disease (AD). In this new study, the researchers took blood samples from both AD patients and healthy controls, then isolated critical immune cells called macrophages from the blood.

Macrophages are responsible for eating-up amyloid beta and other waste products in the brain and body. The team incubated the macrophages with amyloid-beta and added either an active form of vitamin D3 (1alpha,25–dihydroxyvitamin D3) or an active form of the omega-3 fatty acid DHA (resolvin D1) to some of the cells to gauge the effect they had on inflammation and amyloid beta absorption.

In the AD patients' macrophages, both compounds were found to improve the ability of these immune cells to break-down amyloid beta, and both inhibited the cell death that usually result from these plaques.

While this study found amazing potential with the respective biologically active forms of these common nutrients, they are unavailable as supplements at this time. The next best thing is to get DHA (an omega-3) and vitamin D3, and let your body convert them to these powerful and bioactive metabolites.

Source: 1α,25-Dihydroxyvitamin D3 and Resolvin D1 Retune the Balance between Amyloid-β Phagocytosis and Inflammation in Alzheimer's Disease Patients

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1 comment:

  1. Alzheimer's disease is known to be treated by nootropic vitamins that contain choline and sulbutiamine which aid in the development of our brain and muscle control through the help of neurotransmitter acetylcholine. Other nutrients that help in the development of our brain can be found in our normal food diet.

    Joseph @ Nootropics


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