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2012-12-07

Vitamin D Slows Pre-Cancerous Growths

We already knew from numerous epidemiological studies that vitamin D can reduce cancer risk. Now, a team of researchers from Canada said they've discovered a new molecular mechanism on how this superstar vitamin provides protection from cancer. They report that the active form of vitamin D (1,25-dihydroxyvitamin D) acts to block cancer formation by several mechanisms that inhibit the production and function of a specific protein (known as cMYC), which is required for cell division.

The research team explains that cMYC drives cell division and is elevated in more than half of all cancers. The new findings, however, suggest vitamin D can alter this situation by not only inhibiting its production, but also accelerating its degradation. Vitamin D was also shown to strongly stimulate the production of an antagonist to cMYC, called MXD1, essentially shutting down cMYC function.

"Our results show that vitamin D puts the brakes on cMYC function, suggesting that it may slow the progression of cells from premalignant to malignant states and keep their proliferation in check,” said the lead researcher.

We hope that our research will encourage people to maintain adequate vitamin D supplementation and will stimulate the development of large, well-controlled cancer chemoprevention trials to test the effects of adequate supplementation," he added.

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Source: Vitamin D receptor as a master regulator of the c-MYC/MXD1 network

Other posts on vitamin D:

1 comment:

  1. Nice healthy review you have shared on vitamin D. Thanks for your great support on this issue.

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