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Calcium Supplements Reduce the Risk of Hyperparathyroidism

Here's another positive study backing calcium intake. A prospective cohort study including 58,354 females with no history of primary hyperparathyroidism, aged 39-66, followed over a 22 year period, found that calcium intake may be associated with a reduced risk of primary hyperparathyroidism in women.

Hyperparathyroidism is the most common cause of hypercalcemia (excessive levels of blood calcium) and the third most common endocrine disorder in the United States. When the parathyroid glands that secrete too much parathyroid hormone, the body starts to mobilize the calcium in the bones, which leads to increasingly poor bone density, and host of other secondary effects, like kidney stones, and increased risk of high blood pressure and stroke.
Calcium intake was assessed every 4 years via questionnaire. After adjusting for age, body mass index, race, and other factors, the relative risk of primary hyperparathyroidism for women in the group with the highest intake of dietary calcium was reduced. The reduced risk was particularly strong for women taking more than 500 mg/day of calcium supplements (compared with no calcium supplements).

Results suggest that increased calcium may be independently associated with a reduced risk of primary hyperparathyroidism in women. Just remember to take your vitamin K if you're calcium supplements.

As an aside, I should mention another new study that I've decided not to dedicate an entire post to--this one showed that supplementation with 1000 IU/day of vitamin D supressed parathyroid hormone. So looks like the old one-two combo of calcium with vitamin D continues to show positive benefits despite a few unfavourable studies in the past few years.

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  1. Thanks for the newest article on Hyperparathyroidism.

    I have taken calcium supplements for many years. But as with most things, 'a little knowledge is a dangerous thing'. I didn't really know the importance of taking vitamin D3 until a few years ago and most recently the need for Vitamin K2 (as well as magnesium) for proper assimilation.

    I had a parathyroidectomy done this past June at age 62. And I think the most important thing anyone can take away from your article is the importance of taking Vitamin K2 MK7 with calcium and D3 (I would also add a good chelated magnesium from Albion Labs). I shudder to think if I have laid down calcium in my soft tissue and arteries due to being 'half smart' with my calcium dosing. But I am now on 120 mcg VitaminK-2 daily as well as nattokinase to protect against blood clots. I may have to take a therapeutic dose down the road of Vitamin K2 to clear out any calcification but I wanted to start out with a protective dose first and go from there. The beauty of Vitamin K-2 (MK7) is that it is able to put calcium where it belongs in the bones and keep it out from where it doesn't in the soft tissue and arteries.

    Many thanks for your great website, KNOW GUFF, and articles as I am a newbie to your site. Keep up the good work!

    1. You're absolutely right, a little bit of knowledge IS a dangerous thing. In reality, however, who really knows much of anything? "Knowledge" is relative, and to get philisophical, it's an illusion. :)

      Thanks for sharing your story!


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