Thanks for visiting! My goal here is to discuss the latest scientific research to separate the good from all that "guff" in nutritional sciences and all aspects of human health. Because the more you Know, well...the more you Know!

Looking for a specific post? You can browse the Most Read Posts, the Blog Archives, or use the Search function in top left of this page. Thanks for your support and stay healthy!

Monthly 3D Poll


Ubiquinol Improves Semen for Infertile Men

Recently, as a joke, I sent a friend a text message with an R-rated (maybe a risque 18A-rated) picture of adults in a suggestive position (yeah, I know, juvenile right?). The context in which it was sent doesn't matter...it was just bad timing, as the text was delivered as his 8 and 6 year old sons were playing on his iPhone.

Then, as I reflected on my lack of maturity and the corruption of innocent minds (but remember, it was R-rated, not X-rated, so I didn't feel that bad), I came to the conclusion I shouldn't feel bad at all!

In Toronto, we're having another "Summer of the Gun." Lots of gun violence. Then you consider that kids as young as 4 or 5 are allowed to play with toy guns, swords, and other weapons. Even worse, many parents allow kids to watch violence on TV or video games at young ages.

Can someone explain why the act of love between two (or more, if you're into that kinda stuff) consenting adults--something natural, amazing, and pleasurable--is something we shield and protect kids from, yet it's OK for them to watch violence and play with weapons?

I believe we should be teaching kids about sex and acts of love before violence, murder, and war. Don't get me wrong here...I'm not suggesting 6 year olds are ready to know about sex, just that they should NOT learn about violence or weapons (whether it's guns, swords, or Lego catapults...their all designed for murder) BEFORE they learn about sex. I'm also not necessarily suggesting we introduce sex to kids any earlier than it is now, but we should be delaying the introduction of violence until their teen (or tween) years.

I really don't like the fact that my son learned about World War I (as a part of Remembrance Day) as early as Grade 1 or 2, but it'll be a number of years before they teach him about sex.

Teach love, not war. So with that, I move onto today's study...

Does ubiquinol create super sperm?
A double-blind, placebo-controlled, randomized study involving 228 men with unexplained infertility found that ubiquinol (the reduced form of CoQ10) may be effective in improving fertility outcomes in men with idiopathic oligoasthenoteratozoospermia (try saying that even just once fast).

Subjects received either 200 mg ubiquinol daily by mouth or placebo for 26 weeks. All participants were followed for another 12-week off-drug period.

The ubiquinol group had increased sperm density, motility and morphology compared to placebo. During the 12-week off-drug period, semen parameters gradually returned to baseline values but those who took ubiquinol retained improved sperm density and sperm motility. Results suggest ubiquinol supplementation may be effective for improving sperm density, sperm motility and sperm morphology in men with unexplained oligoasthenoteratozoospermia.

Source: Effects of the Reduced Form of Coenzyme Q10 (Ubiquinol) on Semen Parameters in Men with Idiopathic Infertility: a Double-Blind, Placebo Controlled, Randomized Study

CoQ10/ubiquinol is being used increasingly frequently for female infertility, especially in the cases where the cause is just simply older age (women have lower chance of successful pregnancy and increased risk of birth defects as they age). Based on previous in vitro and animal studies, there is exciting potential with this therapy--with human studies currently underway.

Now this study (and some previously conducted case studies) suggest CoQ10/ubiquinol is also great for males as well (this makes sense though and I'm surprised this hasn't been more extensively studied in the past).

Remember, vitamin D also seems to help as I discussed in THIS post.

Related posts on CoQ10/ubiquinol:

Click HERE to subscribe to Know Guff by email


  1. Based on previous research, I've already been prescribing CoQ10 for my male patients. This is not really new as you say in your last paragraph. But good article and I agree with you on the violence vs. sex.

    1. Previous research was conducted using ubiquinone (the standard, oxidized CoQ10). While the research overall is limited for ubiquinol, the research to date for various health conditions have convincingly demonstrated that ubiquinol is much better therapeutically than ubiquinone.

      While I, in no way, want to dictate how you practice, I would highly recommend you look into the studies on ubiquinol.

      All I've been able to dig up for ubiquinone was one human clinical trial published in 2009 (Balercia et al. 2009) and some additional case studies.

      The Balercia study was conducted almost identically to this one, with the exception they used 200 mg/day of regular CoQ10 (ubiquinone). So this gives us a good basis for comparison, even though the two forms of CoQ10 weren't studied head-to-head in the same study.

      In the Balercia study, the men really only saw an increase in sperm motility, whereas in this new study on ubiquinol, the men experienced increased sperm density and better morphology, on top of increased motility.

      Of course, I always want to see more research, but based on the available evidence thus far, I'd conclude ubiquinol is going to offer your infertile male patients the best chance for success...in my opinion.

  2. I don't think anybody should have to improve their fertility. With an over populated world thats exponentially growing, infertility may be something purposeful.


Please use your name or alias. Due to a large volume of spam comments (as "Anonymous") all comments from "Anonymous" will be automatically deleted. Thanks.