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Calcium & D3 for Polycystic Ovaries and Kidney Disease

So to close this high-traffic month (this website has had more visitors this month, by far, than any previous month), I'll discuss two recent studies published on the benefits of calcium and vitamin D supplementation. However, before I get to the goods, I must reiterate that for anyone taking calcium supplements, taking a vitamin K2 supplement is mandatory. For those just getting to this blog for the first time, here are some posts I highly encourage you to read:

Now, the first study I'll cover examined the effect of combined calcium and vitamin D3 supplementationon (or placebo) on bone mineral density (BMD) in patients with chronic kidney disease (CKD). BMD was measured at baseline, 12 and 24 months.

Those taking the supplements had increased vitamin D levels from baseline. Analysis demonstrated an overall treatment effect on BMD, with the those taking the supplements showing a lower rate of BMD loss when compared to the placebo group. Results suggest that combined calcium and vitamin D3 supplementation may be effective in reducing rate of BMD loss in women with moderate CKD.

The second study was also examining calcium and D3 supplementation, but this time on symptoms in infertile women with polycystic ovarian syndrome (PCOS).In this case control study, 100 infertile PCOS women were randomly divided into two groups. Group I was treated with 1500 mg/day metformin (a drug to help control blood sugar), and Group II treated with 1500 mg/day of metformin plus calcium (1000 mg/day) and Vitamin D (100000 IU/month) for 6 months.

In the end, this study showed positive effects of calcium & vitamin D supplementation on weight loss, follicle maturation, menstrual regularity, and improvement of hyperandrogenism, in infertile women with PCOS.

  1. The effect of combined calcium and cholecalciferol supplementation on bone mineral density in elderly women with moderate chronic kidney disease
  2. Therapeutic effects of calcium & vitamin D supplementation in women with PCOS
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