Now, researchers in Finland have published the largest study to date investigating fecal transplantation in patients with CDI. The investigators reviewed data from 70 adults who had received up to 12 courses of antibiotics for CDI; most had received 3 to 6 courses. Most stool donors were close relatives of the patient.
Three months post-transplantation, 66 of the 70 patients reported complete resolution of symptoms. The four who did not respond all had the 027 strain of C. difficile -- a virulent strain -- as well as other serious medical illnesses. In the year following transplantation, four additional patients relapsed; two were treated successfully with antibiotics, and two received another fecal transplant. No complications of transplantation were reported.
Other studies on probiotics--administered orally--also show promise against C. difficile...no sh*t required.
Source: Fecal transplantation, through colonoscopy, is effective therapy for recurrent Clostridium difficile infection
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