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The study involved three groups of rats. The first group was fed a standard diet. The second group was treated orally with an antibiotic in their drinking water. The third group was fed a commercially available probiotic supplement that contains Lactobacillus plantarum 299v – a probiotic bacterial strain that suppresses the production of leptin (a protein hormone that plays a key role in appetite and metabolism).
The group fed the probiotic showed a reduction in circulating leptin levels (by 41%), smaller myocardial infarcts (29% reduction in heart damage), and improved mechanical function (23%).
Source: Intestinal microbiota determine severity of myocardial infarction in rats
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