Thanks for visiting! My goal here is to discuss the latest scientific research to separate the good from all that "guff" in nutritional sciences and all aspects of human health. Because the more you Know, well...the more you Know!

Looking for a specific post? You can browse the Most Read Posts, the Blog Archives, or use the Search function in top left of this page. Thanks for your support and stay healthy!

Monthly 3D Poll


Niacin (B3) Being Combined with "Statin" Cholesterol Drugs

Here's a great video sent by a friend to start your work week...
Although lowering LDL cholesterol ("bad" cholesterol) represents the standard of current lipid treatment, increasing HDL cholesterol ("good" cholesterol) has generated increasing interest because of strong evidence that higher HDL concentrations is associated with reduced risk of coronary heart disease.

Niacin is an essential nutrient that has been used to lower cholesterol since the 1950s. In addition to its LDL-lowering effects, niacin is arguably the most effective agent currently available for raising HDL. I say "arguably" since in one study I've read, krill oil seems to have an even better effect (and is also much safer than 1.0 - 1.5 g of niacin, which is the therapeutic range to see the HDL benefits).

Big Pharma has been looking to develop synthetic drugs to increase HDL, without success. In fact, a number of them were in the clinical trial process when they stopped the trials and discontinued further work since the group getting the experimental drugs were experiencing a variety of dangerous side-effects.

Despite its long history as a lipid-altering nutrient, the majority of studies investigating its impact on clinical outcomes are from the pre-statin area ("statins" are the most prescribed drugs in the world and are effective at lowering LDL, but come with some dangerous side-effects themselves). Several studies have demonstrated a beneficial effect of treatment with niacin in combination with statin therapy on surrogate cardiovascular markers (e.g. carotid intima-media thickness).

Now, two large randomized trials will address whether niacin–statin combination therapy is an appropriate therapeutic alternative to statin monotherapy.

I've also heard Big Pharma combining statins with coenzyme Q10 (which is an essential nutrient that's depleted when taking statins), in hopes to minimize the negative side-effects of taking these popular drugs.

Source: The Facts Behind Niacin

Click HERE to subscribe to Know Guff by email

No comments:

Post a Comment

Please use your name or alias. Due to a large volume of spam comments (as "Anonymous") all comments from "Anonymous" will be automatically deleted. Thanks.