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Vitamin D3 Helps Women with Polycystic Ovary Syndrome

Women with polycystic ovary syndrome (PCOS) frequently suffer from metabolic disturbances, in particular from insulin resistance. Accumulating evidence suggests that vitamin D deficiency may contribute to the development of insulin resistance. Therefore, the researches of this study aimed to examine the effect of vitamin D supplementation on metabolic and endocrine parameters in PCOS women.

PCOS women received 20,000 IU of vitamin D3 weekly for 24 weeks (almost 3000 IU daily). At the end, 25-hydroxyvitamin D (blood measurement of vitamin D status) levels significantly increased, and was correlated with a significant decrease of fasting and stimulated glucose and C-peptide levels after vitamin D treatment. Triglyceride and estradiol levels also significantly decreased. There were no changes in androgens.

PCOS women previously affected by menstrual disturbances (30.4% of subjects) reported improvement of menstrual frequency, and those who were oligo- or amenorrhoeic at the start (half of the subjects) reported improvement.

These results suggest that vitamin D treatment might improve glucose metabolism and menstrual frequency in PCOS women

Source: Effect of vitamin D3 treatment on glucose metabolism and menstrual frequency in PCOS women-a pilot study

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