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2011-08-23

Calcium with Phosphorus Reduces Intestinal Permeability

This was an older video I saw many years ago and came across again more recently. So I thought I'd share it with you here. It looks like some high school talent show or something like that. Forget the first act... just pay attention to the second guy (in the orange shirt, starting at about 35 seconds in). The video is inappropriately titled "Breakdancing," which it's not. I'll find another video for you soon that is likely the best breakdancer I've seen. Stay tuned.


Now for the geeky stuff. Here's another positive study on calcium, this time showing that it can reduce intestinal permeability when in the presence of phosphate.

Increased intestinal permeability is associated with several diseases. Previously, it's been shown that dietary calcium decreases colonic permeability in rats. This might be explained by a calcium-phosphate-induced increase in luminal buffering capacity, which protects against an acidic pH due to microbial fermentation. 

Therefore, these researchers investigated whether dietary phosphate is a co-player in the effect of calcium on permeability. 

What was found? The protective effect of dietary calcium on intestinal permeability is impaired if dietary phosphate is low. This is because calcium seems to drag phosphate into the colon, which increases the phosphate concentration in the colon, which is at least part of the mechanism behind the protective effect of calcium on intestinal permeability.

Although I think the most common salts of calcium (in supplements) are citrate and carbonate, I have seen some supplements containing calcium phosphate. Also note that our bones are a type of calcium phosphate, so this is a form of calcium that may be beneficial to more than just bones.


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