In a randomized, double-blind, placebo-controlled, clinical trial involving 67 type 2 diabetic patients, supplementation with a combination of vitamins and minerals was found to be associated with a significant reduction in neuropathic symptoms.
Subjects who received the following for a period of 4 months were found to have a reduction in neuropathic symptoms from 3.96 to 1.0:
- 20 mg/d zinc
- 250 mg/d magnesium
- 200 mg/d vitamin C
- 100 mg/d vitamin E
- 10 mg/d vitamin B1
- 10 mg/d vitamin B2
- 10 mg/d vitamin B6
- 200 microg/d biotin
- 10 microg/d vitamin B12
- and 1 mg/d folic acid
Source: Improving neuropathy scores in type 2 diabetic patients using micronutrients supplementation
In clinical experience, I've also had success with alpha-lipoic acid (using an R+, temperature-stabilized, sustained-release formula). Something else to consider.
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