In this study, 150 mg/day was able to decrease LDL ("bad" cholesterol) levels by 12.7% in only 2 weeks! Further, the effect was most pronounced in the small, dense LDL particles, which have a greater impact on atherosclerosis (plaque formation) than other types of LDL cholesterol.
In addition, induction of gene expression patterns involved in inflammation, cellular differentiation and death were observed (suggesting possible mechanisms for CoQ10's observed anti-cancer effects).
While this is a great study, it had a relatively small sample size and no control group. Even though this is typical for "pilot" studies, I would love to see the next step be a randomized, double-blinded, placebo-controlled clinical trial.
Nonetheless, my experience with ubiquinol has been nothing short of amazing, and anecdotal reports all over the world are suggesting that this is the form of CoQ10 people would get the most therapeutic benefit from.
One last thing I should point out... ubiquinol (but not CoQ10 as ubiquinone) is considered an extremely powerful antioxidant. Why is this important? LDL cholesterol is usually not a problem until it becomes oxidized. By preventing its oxidation (with ubiquinol), even if LDL is present in amounts greater than desired, you essentially neutralize its potential harmful, plaque-forming abilities.
If you're looking to buy a ubiquinol product, just make sure you buy from a reputable brand that guarantees its stability (as ubiquinol is an unstable molecule).
Other posts discussing new CoQ10 studies:
- Ubiquinol Improves Semen for Infertile Men
- CoQ10 Improves Fibromyalgia Symptoms
- CoQ10 for Brain/Head Trauma
- CoQ10 a Potential Therapy for Alzheimer's Disease
- CoQ10 Supplementation Increases Salivary Secretion
- CoQ10 for Fibromyalgia Symptoms
- CoQ10 for Migraine Prevention in Children & Teens
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Source: Ubiquinol-induced gene expression signatures are translated into altered parameters of erythropoiesis and reduced low density lipoprotein cholesterol levels in humans